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New hearing aids Somerset

New hearing aids Somerset

New hearing aids in Somerset at the Keynsham hearing centre. We are used to new hearing aids arriving from various manufacturers all year round, but when something is really new and exciting we love to tell you and our existing clients why we are so excited.

Hearing aids have evolved in recent years. Digital hearing aids have made the devices so small and powerful they are no longer what people expect to see. The huge hearing aid of old is getting less visible these days, the new as powerful hearing aids are now tiny. If you are looking for new hearing aids in Somerset, we are the place for you!

New hearing aids Devon

The tech inside these little wonders are amazing on so many levels. Take one of the many things they can do. They can connect to your mobile phone and you can talk wirelessly without the phone in your hand as if you were talking to a person next to you. The hearing aid is catching your voice and transmitting this to your phone via bluetooth. You can hear perfectly as your hearing aid is in your ear so you don’t have to really listen hard to get what the conversation is. It’s all done without you doing anything. This tech isn’t new, it has been around for some years, but if your hearing aids are not ”Connected” versions, then maybe when you are next due a new set of hearing aids, you can ask to be told of what’s new in this ”Connected” world.

Devon hearing aid centre

Stephen Neal the lead audiologist at Keynsham hearing centre will be happy to show you and explain all about what is new and on offer. He will also show you how you connect your new digital hearing aid with various tech such as mobile phones, IPads, and the T.V.

If you are in need of ear wax removal please watch our ear wax removal video here.

Make your appointment with Stephen Neal now by calling Anita on reception.

Keynsham hearing news:

 

Semtech and Sonova Launch Jointly-Developed Radio System

Digital hearing aids, Devon

Latest Digital hearing aids at the Honiton hearing centre, Devon

Semtech Corporation (Nasdaq: SMTC), a supplier of high-performance analog and mixed-signal semiconductors and advanced algorithms, and Sonova, a developer of hearing care solutions, announced a jointly developed advanced radio system. The ultra-small integrated circuit (IC) is said to be a main component for a new generation of hearing aids, enabling support for multiple radio protocols in the 2.4GHz band, as well as effective operation on very low power, according to the announcement.

New hearing aids Somerset

“This chip allows Sonova to move in a new direction with our hearing aids,” said Marc Secall, director, research & development, wireless, at Sonova. “The breakthrough radio technology and power management are the game changers for hearing aids. It allows them to support a number of applications that have previously not been possible in a hearing aid, all at low power consumption and low supply voltage. Possible applications span from connectivity to any Bluetooth®-enabled audio device (eg, a smartphone or television) to full duplex audio streaming between hearing aids and connectivity to wireless microphones.”

Ear wax removal Somerset

“Semtech continues to innovate and create flexible, reliable solutions for challenging applications associated with the best radio frequency connectivity at the lowest power and 0.8V supply voltage,” said Jean-Paul Bardyn, vice president of research and development of Semtech’s wireless and sensing products group. “Sonova has long been a leader for hearing devices. By implementing Semtech’s technology and enabling access to the Cloud, we believe that these devices will enrich the IoT-connected solutions which Semtech is serving with LoRa Technology.”

Source: Semtech, Sonova

Images: Semtech, Sononva

Ear wax removal Radstock

Ear wax removal Radstock

Ear wax removal for Radstock is available at the Keynsham hearing centre between Bath and Bristol. Run by Stephen Neal the Keynsham centre covers the whole of Somerset and Wiltshire.  If you are suffering from ear wax issues or in need of a hearing test please book your appointment with Anita at reception.

Out of hours appointments are available at a premium price, there are very limited spaces, pleas call Anita on reception to organise an out of hours ear wax appointment.

To find out more about ear wax removal using the Microsuction technique please click here.

Ear wax removal Radstock

 

Stephen Neal ear wax removal news:

Researchers Restore Hearing via Gene Therapy in Deaf Mouse Model

Published on 

In collaboration with the universities of MiamiColumbia, and San Francisco, scientists from the Institut Pasteur, InsermCNRSCollège de FranceSorbonne University, and the University of Clermont Auvergne have managed to restore hearing in an adult mouse model of DFNB9 deafness, a hearing disorder that represents one of the most frequent cases of congenital genetic deafness, Institut Pasteur announced on its website. Individuals with DFNB9 deafness are profoundly deaf as they are deficient in the gene coding for otoferlin, a protein which is essential for transmitting sound information at the auditory sensory cell synapses. By carrying out an intracochlear injection of this gene in an adult DFNB9 mouse model, the scientists successfully restored auditory synapse function and hearing thresholds to a near-normal level. These findings, published in the journal PNAS, open up new avenues for future gene therapy trials in patients with DFNB9.

The left panel is a schematic representation of the human ear. Sound waves are collected by the outer ear made up of the pinna and ear canal. The middle ear, composed of the eardrum and ossicles, transmits sound waves to the inner ear, which features the cochlea – the hearing organ responsible for transmitting auditory messages to the central nervous system. The right panel shows an immunofluorescence image of the auditory sensory epithelium within an injected cochlea. The inner hair cells have been stained for otoferlin in green. Otoferlin is detected in almost all of these cells. The inset is a high magnification area showing an inner hair cell that has not been transduced. © Institut Pasteur

The left panel is a schematic representation of the human ear. Sound waves are collected by the outer ear made up of the pinna and ear canal. The middle ear, composed of the eardrum and ossicles, transmits sound waves to the inner ear, which features the cochlea – the hearing organ responsible for transmitting auditory messages to the central nervous system. The right panel shows an immunofluorescence image of the auditory sensory epithelium within an injected cochlea. The inner hair cells have been stained for otoferlin in green. Otoferlin is detected in almost all of these cells. The inset is a high magnification area showing an inner hair cell that has not been transduced. © Institut Pasteur

Over half of nonsyndromic profound congenital deafness cases have a genetic cause, and most (~80%) of these cases are due to autosomal recessive forms of deafness (DFNB). Cochlear implants are currently the only option for recovering hearing in these patients.

Ear wax removal Radstock

Adeno-associated viruses (AAVs) are among the most promising vectors for therapeutic gene transfer to treat human diseases. AAV-based gene therapy is a promising therapeutic option for treating deafness but its application is limited by a potentially narrow therapeutic window. In humans, inner ear development is completed in utero and hearing becomes possible at approximately 20 weeks of gestation. In addition, genetic forms of congenital deafness are generally diagnosed during the neonatal period. Gene therapy approaches in animal models must therefore take this into account, and gene therapy efficacy must be demonstrated following a gene injection when the auditory system is already in place. In other words, therapy must reverse existing deafness. The team led by Saaïd Safieddine, a CNRS researcher in the Genetics and Physiology of Hearing Unit (Institut Pasteur/ Inserm) and coordinator of the project, used a mouse model of DFNB9, a form of human deafness that represents 2-8% of all cases of congenital genetic deafness.

Ear wax removal Radstock

DFNB9 deafness is caused by mutations in the gene coding for otoferlin, a protein that plays a key role in transmitting sound information at the inner hair cell synapses. Mutant mice deficient in otoferlin are profoundly deaf as these synapses fail to release neurotransmitters in response to sound stimulation, despite the absence of detectable sensory epithelial defects. DFNB9 mice therefore constitute an appropriate model for testing the efficacy of viral gene therapy when it is administered at a late stage. However, as AAVs have limited DNA packaging capacity (approximately 4.7 kilobase (kb)), it is difficult to use this technique for genes whose coding region (cDNA) exceeds 5 kb, such as the gene coding for otoferlin, which has a 6 kb coding region. The scientists have overcome this limitation by adapting an AAV approach known as dual AAV strategy because it uses two different recombinant vectors, one containing the 5’-end and the other the 3’-end of the otoferlin cDNA.

A single intracochlear injection of the vector pair in adult mutant mice was used to reconstruct the otoferlin coding region by recombining 5′ and 3′-end DNA segments, leading to long-term restoration of otoferlin expression in the inner hair cells, and then restored hearing.

The scientists have therefore obtained initial proof of the concept of viral transfer of fragmented cDNA in the cochlea using two vectors, showing that this approach can be used to produce otoferlin and durably correct the profound deafness phenotype in mice.

The outcomes achieved by the scientists suggest that the therapeutic window for local gene transfer in patients with DFNB9 congenital deafness could be wider than thought, and offers hope of extending these findings to other forms of deafness. These results are the subject of a patent application filed.

In addition to the institutions mentioned in the first paragraph, this research was funded by the French Foundation for Medical Research, the European Union (TREAT RUSH), and the French National Research Agency (EargenCure and Lifesenses LabEx).

Original Paper: Akil O, Dyka F, Calvet C, et al. Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model. PNAS. 2019. DOI: https://doi.org/10.1073/pnas.1817537116

Source: Institut Pasteur, PNAS

Image: Institute Pasteur

Ear wax removal Radstock